OFLOSIN

Ofloxacin, Metronidazole Benzoate & Simethicone Suspension – Ofloxacin + metronidazole + simethicone suspension is mainly used to treat diarrhea. Ofloxacin+metronidazole+simethicone is an anti-diarrheal medicine used to treat diarrhea in children. Diarrhea is defined as an illness that causes you to get rid of waste material from your body very often and in a more liquid form than usual. It can be temporary or long-term. Most often, diarrhea can be caused by different types of bacteria. This suspension is intended to treat gastrointestinal and urinary problems caused by susceptible bacteria and parasites, relieve symptoms, and promote recovery. To achieve optimal treatment results, it is very important to follow the prescribed dosage and duration.

Mechanism of Ofloxacin, Metronidazole Benzoate and Simethicone Suspension

Ofloxacin, metronidazole benzoate, and simethicone suspension is a combination medication used to treat a variety of bacterial and protozoan infections and symptoms such as abdominal pain and gas. Here’s a breakdown of each component and its mechanism:

1. Ofloxacin: Ofloxacin is a fluoroquinolone antibiotic. It works by inhibiting bacterial enzymes and, ofloxacin prevents bacterial DNA synthesis and ultimately leads to the death of the bacterial cell.
2. Metronidazole Benzoate: It works by entering the cells of bacteria and protozoa and damaging their DNA, causing cell death. Metronidazole is particularly effective against anaerobic bacteria and some protozoa. Its mechanism of action involves the reduction of this nitro group by intracellular electron transport proteins, causing the formation of reactive intermediates that disrupt DNA structure and function, causing cell death.
3. Simethicone: It breaks up large gas bubbles into smaller ones, making it easier for them to leave the body through belching or passing gas. Simethicone is not absorbed into the bloodstream or metabolized in the body; it works topically in the digestive tract to relieve gas and bloating.

Combining these three components in a suspension allows for the treatment of abdominal discomfort and gas. 

Uses of Oflaxacin, Metronidazole Benzoate & Simethicone Suspension

Ofloxacin is an antibiotic commonly used to treat bacterial infections, including urinary tract infections, respiratory infections, and skin infections. Metronidazole benzoate is an antiprotozoal and antibiotic medication that is effective against anaerobic bacteria and certain parasites, making it useful in the treatment of conditions such as bacterial vaginosis, pelvic inflammatory disease, and certain types of diarrhea. Simethicone, on the other hand, is an anti-gas medication that helps relieve symptoms associated with excess gas in the digestive tract, such as bloating, discomfort, and flatulence. When these drugs are combined in the form of a suspension, they provide a comprehensive approach to the treatment of a wide range of bacterial infections, gastrointestinal discomfort, and related symptoms.

Side Effects

Like any medication, this drug also causes some possible side effects:

• Nausea
• Vomiting
• Headache
• Loss of appetite
• Dryness in mouth

Precautions

• Before administering this medicine, let your doctor know about your child health’s condition, including current medications and previous medical history
• Dairy products should be avoided
• Do not stop taking the medicine even if your child feels better, but finish the entire course of treatment.