GLIMIRAP-M1

Glimepiride & Metformin HCL (Sustained-Release) Tablets – It cures type 2 diabetes. This tablet is a combination of two diabetes medications; Glimepiride and metformin. Type 2 diabetes is a chronic (long-term) disease that affects the body’s process of glucose. Type 2 diabetes is a heterogeneous disease, and patients are at increased risk for macrovascular complications, peripheral artery disease, stroke/transient ischemic attack, and microvascular complications due to inadequate glycemic control. This mixed tablet supports patients with type 2 diabetes in balancing their blood sugar. It works best when used in conjunction with a balanced diet and regular workout. It is available in the Indian market under the brand GLIMIRAP-M1, effectively manufactured and supplied by Rapidchem Healthcare.

Mechanism of Glimepiride and Metformin HCL Tablets

Glimepiride and Metformin HCL tablets help your body use insulin more effectively and lower blood sugar. Here is a brief summing up of how each drug works in combination tablet form:

• Glimepiride: Glimepiride is an antidiabetic medication belonging to the sulfonylurea class. It works by stimulating the pancreas to release insulin, which helps in controlling the blood sugar. Glimepiride binds to specific receptors on pancreatic beta cells, which increases insulin secretion. 
• Metformin: Metformin belongs to a biguanide diabetes medication. It works primarily by reducing and balancing glucose production in the liver and also increases insulin sensitivity in peripheral tissues. It improves the uptake of glucose from the blood into the cells and lowers blood glucose.  

The combination of glimepiride and metformin HCL in one tablet is useful because it addresses different aspects of glucose control in people with type 2 diabetes. Glimepiride helps stimulate the release of insulin from the pancreas, especially after meals, when blood sugar tends to rise. On the other hand, metformin reduces hepatic glucose production and improves insulin sensitivity throughout the body. Thus, Glimepiride and Metformin HCL tablets improve insulin secretion and reduce insulin resistance, thereby helping to achieve better glycemic control in diabetic patients.

Uses of Glimepiride and Metformin HCL Tablets

Glimepiride and Metformin HCL Tablets are known to treat type 2 diabetes mellitus. Here are the primary uses and benefits of GLIMIRAP-M1

• These combinations are intended to improve glucose control in people whose blood sugar levels cannot be controlled with either drug alone.
• They offer the convenience of using two different mechanisms of action in one tablet, which can simplify patient regimens.
• It is usually used in conjunction with lifestyle changes such as diet and exercise to effectively treat diabetes.
• By increasing insulin sensitivity, glimepiride and metformin can help reduce the amount of insulin the body needs to control blood sugar. 

Possible Side Effects

Glimepiride and metformin hydrochloride tablets are generally safe to use when used under a doctor’s guidance. However, a slight carelessness or overdose can cause side effects to the patient. Side effects associated with the use of Glimepiride + Metformin HCL tablets are as follows:

• Stomach Pain
• Nausea
• Diarrhea
• Vomiting
• Headache
• Metallic Taste 

Note: These are some of the mild side effects that do not require medical attention as they go away as the body gets used to the medication. But if they do not contact the doctor. 

Precautions

• Keep monitoring your blood sugar levels while you are on this medicine
• It is not advised to take this medicine without food as it may cause an upset stomach
• Reach out to your doctor immediately if you experience the side effects or any other suspicious symptoms